Search results for "Gene Expression Profiles"

showing 3 items of 3 documents

Gene expression changes after parental exposure to metals in the sea urchin affect timing of genetic programme of embryo development

2021

Simple Summary Intergenerational and transgenerational effects, in which exposure to stressors in a parental generation affects the phenotype of the offspring have been connected to anthropic impacts on biological systems. Therefore, environmental stress experienced inside a generation, particularly during gametogenesis, may lead to erroneous patterns in their offspring just emerging at early developmental stages. In this scenario, the sea urchin embryo represents a suitable model for integrating analyses of gene expression through embryogenesis with developmental alteration induced by environmental stressors. Herein we provide pieces of evidence for the alteration of the gene regulatory ne…

0301 basic medicineSea urchinanimal structuresOffspringIntergenerational effectsSettore BIO/11 - Biologia Molecolare010501 environmental sciencesEmbryo development01 natural sciencesArticleGeneral Biochemistry Genetics and Molecular BiologyAndrology03 medical and health sciencesbiology.animalGene expressionParental exposureEpigeneticslcsh:QH301-705.5GeneSea urchin0105 earth and related environmental sciencesGeneral Immunology and MicrobiologybiologyEmbryogenesisEmbryoPhenotype030104 developmental biologyGene expression profileslcsh:Biology (General)embryonic structuressea urchin; redox homeostasis; parental exposure; intergenerational effects; embryo development; gene expression profilesGeneral Agricultural and Biological SciencesEmbryo development Gene expression profiles Intergenerational effects Parental exposure Redox homeostasis Sea urchinRedox homeostasis
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Neural Crest-Derived Chondrocytes Isolation for Tissue Engineering in Regenerative Medicine

2020

Chondrocyte transplantation has been successfully tested and proposed as a clinical procedure aiming to repair articular cartilage defects. However, the isolation of chondrocytes and the optimization of the enzymatic digestion process, as well as their successful in vitro expansion, remain the main challenges in cartilage tissue engineering. In order to address these issues, we investigated the performance of recombinant collagenases in tissue dissociation assays with the aim of isolating chondrocytes from bovine nasal cartilage in order to establish the optimal enzyme blend to ensure the best outcomes of the overall procedure. We show, for the first time, that collagenase H activity alone …

BiologyRegenerative MedicineRegenerative medicineArticleChondrocyte03 medical and health sciencesChondrocytes0302 clinical medicineTissue engineeringmedicineAnimalsHumanscell transplantationlcsh:QH301-705.5030304 developmental biology0303 health sciencesnasal chondrocytesTissue Engineeringgene expression profilesCartilageNeural crestCell DifferentiationGeneral Medicinetissue dissociationIn vitro3. Good healthCell biologyTransplantationmedicine.anatomical_structurelcsh:Biology (General)Neural CrestcollagenasesCollagenaseCattle030217 neurology & neurosurgerymedicine.drugCells
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Gene Expression Analysis Uncovers Similarity and Differences Among Burkitt Lymphoma Subtypes.

2011

Abstract Abstract 2494 Background. Burkitt lymphoma (BL) is currently listed in the WHO classification of lymphoid tumors as a single genetic and morphological entity with variation in clinical presentation. In particular, three clinical subsets of BL are recognized: endemic (eBL), sporadic (sBL) and immunodeficiency associated (ID-BL). Each affects different populations and can present with different features. So far, possible differences in their gene expression profiles (GEP) have not been investigated. In this study we aimed to 1) assess whether BL subtypes present with differences in their GEP; 2) investigate the relationship of the different BL subtypes with the non-neoplastic cellula…

Gene Expression Profiles; burkitt lymphomaGene expression analysieducationTransplantation HeterologousImmunologyMice NudeBiologyburkitt lymphomaBiochemistryBurkitt lymphoma.Micehemic and lymphatic diseasesCell Line TumormedicineAnimalsCluster AnalysisHumansRegulation of gene expressionGeneticsGene Expression ProfilesGENE EXPRESSION PROFILEMicroarray analysis techniquesGene Expression ProfilingGerminal centerCell BiologyHematologymedicine.diseaseMicroarray AnalysisPhenotypeLymphomaGene expression profilingTransplantationGene Expression Regulation NeoplasticPhenotypeBurkitt's lymphomaNeoplasm TransplantationGene expression analysis;Burkitt lymphoma.
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